4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18230 | MAC glucuronide linker-1 | Others | |
MAC glucuronide linker-1 is a nonclaevable ADC linker for antibody-drug-conjugations (ADCs). | |||
T18722 | MAC glucuronide α-hydroxy lactone-linked SN-38 | Others | |
MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a cytotoxic drug linker that maintains a stabilized lactone form, showing efficacy against L540cy and Ramos cells, with IC50 values of 99 and ... | |||
T18231 | MAC glucuronide linker-2 | Others | |
MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1]. | |||
T18538 | MAC glucuronide phenol-linked SN-38 | Others | |
MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1]. |